Shifting tactics on making the rooms workable. The irritation and infection, which I at first thought was an illness from the journey, doesn't appear to be particulate-based. The air is stale, especially in the afternoon, but the summertime 2.5 numbers are negligible. (There have been places during this journey where the meter has gone to purple--approximately 3-4x what's usually considered a lock-the-doors crisis stateside.) Perhaps it's a dust mite thing -- I did clear almost an inch of packed dust off of the climate control filters when I arrived. Bagged the curtains, rolled the rug, and covered the mattress in a plastic tarp. Will see if the symptoms persist.
It does have a psychological effect. Bit off the game. Onward.